Acronym of STFU

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Shut The Fuck Up

Southern Tenant Farmers' Union

Super Time Force Ultra

Say, Thanks for Understanding

Special Task Force Unit (gaming)

Short-Term Follow-Up (pharmaceutical study)

Stop Tickling Furry Unicorns

Shut the Freak Up (polite form)

Stop Trolling for Unicorns

Star Trek Federation University

Scrawny Two-Faced Underling

Sir, That's Freakin Ugly (polite form)

Samurai Training Finished Unsuccessfully

Show Them Fury Unleashed

Save the Flying Unicorns